RNAi and RNA Reagents
ABclonal Technology Phospho-p90Rsk/RSK1/RPS6KA1-S363 Rabbit pAb
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Sigma Aldrich Fine Chemicals Biosciences PI3 Kinase (p110α/p85α) Protein
PI3 Kinase (p110α/p85α) Protein | Active complex of N-terminal His6-tagged recombinant full-length human p110α & untagged, recombinant, full length, human p85α. For use in Kinase Assays, 20ug
Cell Signaling Technology PathScanR Total CREB Sandwich ELISA Kit 10 Kit
PathScanR Total CREB Sandwich ELISA Kit 10 Kit
Cellecta Inc Mouse Genome-Wide CRISPRi sgRNA Library, 200ug Plasmid
Mouse Genome-Wide CRISPRi sgRNA Library, 200ug Plasmid
ABclonal Technology 5'App-T4 DNA Ligase
5App-T4 DNA Ligase is a mutant of T4 DNA Ligase without adenylation function, which can specifically ligates the pre-adenylated 5? end of DNA or RNA to the 3? end of DNA. This enzyme does not require ATP as a cofactor for ligation, but requires a pre-adenylated substrate. This enzyme reduces background ligation (chimera formation) during NGS library construction, because it can only use 5 preadenylation adapter to the DNA fragments.
HORIZON DISCOVERY BIOSCIENCES LIMITED EDIT-R HU SYNTHETIC AAVS1 SGRN
NC3854388 EDIT-R HU SYNTHETIC AAVS1 SGRN
HORIZON DISCOVERY BIOSCIENCES LIMITED EDIT-R STAG2-SG502 SGRNA 10NM
NC3854412 EDIT-R STAG2-SG502 SGRNA 10NM
Aldevron T7 RNA Polymerase, 130ug
130ug dispense of wild type T7 RNA Polymerase. T7 RNA Polymerase catalyzes synthesis of RNA in the presence of a DNA template containing the T7 phage promoter.
HORIZON DISCOVERY BIOSCIENCES LIMITED OTP HUMAN PCSK9 255738 SIRNA
NC2216259 OTP HUMAN PCSK9 255738 SIRNA
HORIZON DISCOVERY BIOSCIENCES LIMITED ON-TARGETPLUS NON-TARGETING SI
ON-TARGETplus Non-targeting siRNA #2, 20 nmol
HORIZON DISCOVERY BIOSCIENCES LIMITED HUMAN MAPK1 5594 SIRNA - SMA
NC3825784 HUMAN MAPK1 5594 SIRNA - SMA
Genscript Corporation GLP-1R mFc Chimera Human
The GLP1R a GPCR is found on pancreatic beta cells and brain neurons It regulates blood sugar by enhancing insulin secretion In humans it is encoded by the gene GLP1R on chromosome 6 GLP1R is part of the glucagon receptor GPCR family and comprises an extracellular domain that binds the C-terminal helix of GLP-1 and a transmembrane domain that binds the N-terminal region of GLP-1 The TMD domain contains polar residues that regulate biased signaling while the transmembrane helical boundaries and extracellular surface trigger biased agonism
Genscript Corporation CD47 hFc Chimera Mouse
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRP ) CD-47 acts as a don t eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers
Genscript Corporation CD52 hFc Chimera Human
CD52 also known as CAMPATH-1 antigen HE5 and gp20 is a cell surface glycoprotein that can be targeted to induce immune suppression by complement-mediated cell lysis Mature human CD52 is a 12 amino acid peptide that is tethered to the cell surface with a GPI linkage CD52 may play a role in carrying and orienting carbohydrate as well as having a more specific role
Genscript Corporation TNFRSF12A/TWEAKR hFc Chimera
Thyroid cancer (TC) is the most well-known endocrine neoplasia as well as a common malignant tumor in the head and neck TNFRSF12A expression may be a potential useful prognostic molecular biomarker of bad survival in thyroid cancer in addition PPAR signaling pathway insulin signaling pathway mTOR signaling pathway may be the key pathway controlled by TNFRSF12A in thyroid cancer Further experimental ought to be performed to demonstrate the biologic effect of TNFRSF12A